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EFFECTS OF POLYPHOSPHATE MIXED IN ACRYLIC RESIN ON THE ATTACHMENT AND GROWTH OF ORAL BACTERIA

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Abstract

ÀÚ°¡ÁßÇÕÇü ¾ÆÅ©¸±¸¯ ·¹Áø¿¡ polyP¸¦ È¥ÇÕÇÏÁö ¾ÊÀº ´ëÁ¶±º, ±×¸®°í ·¹Áø ºÐ¸»¿¡ ´ëÇÑ polyp(»ç½½±æÀÌ 13°ú 18ÀÇ È¥ÇÕ¹°ÀÎ Calgon)ÀÇ ¹«°Ôºñ¸¦ 1%·Î È¥ÇÕÇÑ polyP 1%±º, 2% È¥ÇÕÇÑ polyP 2%±º ¹× 3% È¥ÇÕÇÑ polyP 3%±ºÀ¸·Î ºÐ·ùÇÏ¿© °æÈ­½ÃŲ ÈÄ, °æÈ­µÈ °¢°¢ÀÇ ·¹Áø°ú ½ÇÇè±ÕÁÖ S. mutans GS5, S. Sobrinus 6715, S. gordonii G9B ¹× Challis, ±×¸®°í P. gingivalis 2561°ú Candida albicans ATCC90027À» ´ë»óÀ¸·Î ·¹ÁøÇ¥¸é¿¡ ´ëÇÑ ¹Ì»ý¹°µéÀÇ ºÎÂøÀÇ Á¤µµ, ¼ºÀå ¾ïÁ¦È¿°ú ¹× Á¢ÃË°¢ÀÇ º¯È­¸¦ °üÂûÇÏ¿© ±× °á°ú·Î ¹Ì·ç¾î ¾ÆÅ©¸±¸¯ ·¹Áø¿¡ Æ÷ÇÔµÈ polyP´Â ±¸°­ ¹Ì»ý¹°¿¡ ´ëÇØ Á÷Á¢ÀûÀ¸·Î °­ÇÑ Ç×±Õ È¿°ú¸¦ ³ªÅ¸³»Áö´Â ¾Ê´Â °ÍÀ¸·Î ÆǴܵdzª ¹Ì»ý¹°ÀÇ ºÎÂø ƯÈ÷ ¿ì½Ä¿øÀαÕÀÎ mutans streptococciÀÇ ºÎÂøÀ» ¹æÇØÇÏ´Â °ÍÀ¸·Î °¡´ÆµÇ¸ç, ÀÌ´Â polyPÀÇ Ã·°¡¿¡ ÀÇÇÑ ¾ÆÅ©¸±¸¯ ·¹Áø Ç¥¸é¿¡¼­ ÀϾ ¼Ò¼ö¼ºÀÇ º¯È­°¡ ÀϺΠ°ü¿©ÇÏ´Â °ÍÀ¸·Î ¿©°ÜÁø´Ù. PolyP°¡ È¥ÇÕµÈ ¾ÆÅ©¸±¸¯ ·¹ÁøÀÇ ÀåÂøÀº ÀϹÝÀûÀÎ ¾ÆÅ©¸±¸¯ ·¹ÁøÀ¸·Î Á¦ÀÛµÈ °¡Ã¶¼º ÀåÄ¡¸¦ ÀåÂøÇÑ ÈÄ ³ªÅ¸³¯ ¼ö ÀÖ´Â ¿ì½Ä ÀÌȯÀÇ °¡´É¼ºÀ» °¨¼Ò½Ãų ¼ö ÀÖ´Â ÀÓ»óÀû Àû¿ë °¡´É¼ºÀ» Á¦½ÃÇÏ¿´´Ù°í ¿©°ÜÁø´Ù.
The purpose of this present study was to develop a new way of self-curing acrylic resin, using commercially available polyphosphate. Calgon, which is known to be antimicrobial and safe.
For the study, polyphosphate(polyP) was blended with acrylic powder and devided into four groups as follows: no polyP(control), 1% polyP. 2% polyP, and 3% polyP. For the experiment, Streptococcus mutans GS5, Streptococcus sobrinus 6715, Streptococcus gordonii G9B and Challis, Porphyr¡Æomonas gingivalis 2561, and Candida albicans ATCC 90027 were used.
Resin specimens in each group were tested in vitro for the purpose of investigating the effect of polyP on the microbial attachment, growth and hydrophobicity of the resin surface.
The results were as follows.
1. PolyP added to the acrylic resin decreased attachment of S. mutans GS5, S. sobrinus 6715. S. gordonii G9B. The greater binding inhibition was found in acrylic resin polymerized with polyP at higher concentrations.
2. The addition of polyP to acrylic resin failed to significantly affect the growth of the tested microorganisms.
3. The addition of polyP to acrylic resin seemed to reduce hydrophobicity of the acrylic resin.
PolyP in acrylic resin does not seem to exert a direct antibacterial activity, but rather inhibit attachment of oral bacteria, especially mutans streptococci to saliva-coated acrylic resin. The acrylic resin reduces attachment of streptococci may be due to the decreased hydrophobicity caused by polyP added to the resin. PolyP may be included to acrylic resin to inhibit dental caries which often occurs when removable acrylic resin appliance is placed.

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Acrylic resin;Polyphosphate;Bacterial attachment

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